- Dysphagia
- Difficulty swallowing that can have numerous causes, but is seen in scleroderma.
- Cor pulmonale
- Pulmonary heart disease is damage to the right ventricle of the heart caused by resistance to blood flow in the lung -- as a result of pulmonary hypertension or restrictive lung disease (pulmonary fibrosis).
- Pulmonary hypertension
- An increase in blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries.
- Usual interstitial fibrosis
- A form of progress fibrosis of the lung caused by idiopathic pulmonary fibrosis or collagen vascular disorders.
- Malar rash
- A facial rash in a butterfly pattern, often seen in lupus erythematosus (but is not pathognomonic). Malar is Latin for "cheek."
- Raynaud phenomenon
- A vasospastic disorder causing the blanching discoloration of the fingers or toes due to decreased blood supply. Usually idiopathic but can be seen in collagen vascular disorders.
- Antiphospholipid antibodies
- Autoimmune antibodies that induce a hypercoagulable state that can cause arterial or vascular thrombosis. Frequently seen in lupus.
- Acute humoral rejection
- Preformed or induced antibodies against a transplanted organ that leads to microvascular thrombosis.
- Acute cellular rejection
- A T-lymphocyte mediated immune reaction against a transplanted organ that can damage the tubules and vessels within the kidney.
- Chronic rejection
- A form of rejection that occurs over years due to either multiple episodes of acute cellular rejection or other other injury.